Independent reviews · Updated weekly Editorial & affiliate disclosures
HFL Health Findings Lab™

Vitamin B1

Also known as Thiamine, critical for carbohydrate metabolism and neuronal energy production.

Evidence-Based
Fact-Checked
Updated: Oct 02, 2026
Share this ingredient:
Clinical Profile

Quick Reference

Scientific Rating
4.6
/ 5.0
Standardized Form
Thiamine Hydrochloride or Benfotiamine

Thiamine is an essential enzymatic cofactor for the metabolism of glucose and amino acids. It is highly concentrated in skeletal muscle, the heart, and the brain, where it is vital for ATP production. Severe deficiency results in beriberi or Wernicke-Korsakoff syndrome.

Clinical Summary

Clinically used to support healthy energy metabolism and nerve function.

Dosage Guidelines

1.1mg to 1.2mg daily.

Safety & Side Effects

No known toxicity; excess is excreted in urine.

Known Interactions

Diuretics can increase urinary excretion of thiamine.

Scientific References

Medical Disclaimer

The information provided in this clinical review is for educational and informational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment.

*These statements have not been evaluated by the Food and Drug Administration (FDA). This product or ingredient is not intended to diagnose, treat, cure, or prevent any disease.

Always consult your physician or other qualified health provider with any questions you may have regarding a medical condition, or before beginning any new diet, fitness, supplement, or treatment regimen, especially if you have pre-existing medical conditions or are taking prescribed medications.

Share this ingredient:

Get new reviews in your inbox — weekly, never spammy.

Join our community of readers who use Health Findings Lab to cut through supplement marketing noise.