Quick Reference
- Scientific Rating
-
4.7/ 5.0
- Standardized Form
- Pyridoxal-5-Phosphate (P5P)
Vitamin B6 acts primarily in its active form, Pyridoxal-5-Phosphate (P5P). It is an obligate cofactor for over 100 enzymatic reactions, most notably in the synthesis of neurotransmitters (serotonin, dopamine, GABA) and the regulation of homocysteine levels in the blood.
Table of Contents
Clinical Summary
Clinically utilized for supporting mood, reducing morning sickness in pregnancy, and managing homocysteine levels.
Dosage Guidelines
1.3mg to 1.7mg daily.
Safety & Side Effects
Long-term megadosing (over 200mg/day) can cause reversible sensory neuropathy.
Known Interactions
Can reduce the efficacy of levodopa (Parkinson's medication) if not taken with a decarboxylase inhibitor.
Scientific References
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Medical Disclaimer
The information provided in this clinical review is for educational and informational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment.
*These statements have not been evaluated by the Food and Drug Administration (FDA). This product or ingredient is not intended to diagnose, treat, cure, or prevent any disease.
Always consult your physician or other qualified health provider with any questions you may have regarding a medical condition, or before beginning any new diet, fitness, supplement, or treatment regimen, especially if you have pre-existing medical conditions or are taking prescribed medications.